GHK-Cu Rx
One of the better-characterized peptides in skin science, studied for collagen synthesis, wound repair and follicle support.
- Collagen remodeling
- Follicle support
- Wound repair
- Flexible monthly plans
- US-licensed pharmacies
- Clinician-guided dosing
- Pause or cancel anytime
Starting at$69 / mo
- HSA / FSA eligible
- Ongoing, expert support
- Free, discreet shipping
- 100% online
- Topical or injectable?
- For skin-specific goals, topical delivers the compound where it's needed. Injectable is used when the target is broader connective-tissue support.
- How long until I see a difference?
- Collagen remodeling is slow. Eight to twelve weeks is the realistic window, which is why we take standardized photos at baseline.
- Can I use it with retinoids?
- Usually, but alternate nights initially. Using both on the same night can be more irritation than most skin tolerates at first.
Topical use may cause mild irritation or redness, particularly in the first two weeks. Injectable use can cause injection-site reactions. The blue color transfers to fabric readily.
Who this is not for
- Copper accumulation is a theoretical concern with high-dose long-term use
- Not appropriate with Wilson's disease
- Can stain fabric — it's blue
- Not evaluated in pregnancy or breastfeeding
Regulatory status: Compounded. Read our full medical disclaimer.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. This product is compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Actual product packaging may appear differently than shown.
What is GHK-Cu?
GHK is a naturally occurring tripeptide in human plasma that binds copper with high affinity; plasma levels fall sharply with age.
The copper complex appears to signal skin fibroblasts to increase collagen and elastin production while modulating matrix metalloproteinases — the enzymes that degrade them.
Individual results vary. Figures shown are modelled from published literature and aggregated, self-reported member check-ins; they are illustrative and are not a guarantee of outcome. See the evidence tier for this treatment.
days to a fair assessment
90How GHK-Cu works
Week 1
Onboarding, first dose and a check-in on tolerability. Most protocols start below the standard dose so your body has time to adjust.
30 Days
Your first real signal. We review side effects, adherence and any early changes before deciding whether to adjust anything.
3 Months
The window where most measurable change shows up. Repeat labs where the protocol calls for them, and a dose review either way.
6 Months
Trend lines rather than single readings. We compare against your baseline panel and decide whether to continue, adjust or stop.
1 Year and Beyond
Maintenance. The goal is the lowest effective dose you can hold, with twice-yearly labs keeping the protocol honest.
Our research is shaping what comes next
Most providers in this category focus on doing more. We study what happens when the goal is finding the right amount. With a fully in-house care team, longevity researchers, and 17+ protocols graded by evidence tier, we're built to support the bigger picture of your health.
GHK-Cu in skin regeneration and anti-aging
BioMed Research International · 2018
Copper tripeptide and collagen synthesis in human fibroblasts
Journal of Investigative Dermatology · 1993
GHK peptide effects on gene expression in human cells
Oncotarget · 2017
GHK-Cu
treatment insights
Modelled response patterns are trending in the optimal range
Read our clinical trials
Skin & hair and longevity
Our researchers are studying ghk-cu through a longevity-focused lens, exploring how lower-dose protocols may be used in long-horizon care beyond the primary indication.
Read our researchSubscribe & save
Care that starts
with you
$69/month
What's included
- Personalized, clinician-guided plan
- Flexible monthly plans
- Dispensed by a US-licensed pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Third-party potency and sterility testing
How it works
Choosing how you age starts here
- Certified1
Clinician-led
Connect with a clinician
Connect with one of our US-licensed, in-house medical providers with 199+ years of combined clinical experience to make sure treatment is right for you. 100% online. No in-person visit required.
- 2
Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed pharmacy, third-party tested by lot, and shipped to your door in unbranded packaging — cold-chain where the formulation requires it.
- 3
Ongoing support
Adjust as you go
Message your care team whenever something changes. Dose adjustments, side-effect questions and protocol changes are included in your membership — never another appointment, never another fee.
The protocol
- Topical
- Applied nightly to clean skin
- Injectable
- 1–2 mg, 2–3× weekly
- Timeline
- 8–12 weeks before visible change
- Documentation
- Standardized photos at baseline and 90 days
- Storage
- Cool and dark
A good fit if
- Skin firmness and fine-line goals
- Early-stage hair thinning
- Post-procedure recovery support
- You'll give it a full 90 days before judging
Worth knowing
- Copper accumulation is a theoretical concern with high-dose long-term use
- Not appropriate with Wilson's disease
- Can stain fabric — it's blue
- Not evaluated in pregnancy or breastfeeding
Ready when you are
Start GHK-Cu today
Complete a ten-minute intake, get a licensed clinician's review, and find out whether this is right for you — before you pay for anything.