NAD+ Nasal Spray Rx
The same cellular-energy support as the injection, delivered intranasally — a practical option for needle-averse patients and for targeting cognitive symptoms.
- No needles
- Direct nose-to-brain pathway
- Travel-friendly
- Flexible monthly plans
- US-licensed pharmacies
- Clinician-guided dosing
- Pause or cancel anytime
Starting at$49 / mo
- HSA / FSA eligible
- Ongoing, expert support
- Free, discreet shipping
- 100% online
- Is the spray as effective as the injection?
- For whole-body energy, the injection delivers more systemic NAD+. For cognitive symptoms specifically, the nasal route has a delivery advantage. Many patients use both.
- Can I use it with the injection?
- Yes, and it's a common pairing — the spray daily, injections two or three times a week. Your clinician will set the combined total.
- Does it need refrigeration?
- Yes. Keep it in the fridge between uses; it's fine at room temperature for a travel day.
Temporary nasal irritation, a brief metallic taste and mild sinus pressure are the usual reports. These generally settle within the first week of consistent use.
Who this is not for
- Lower systemic exposure than subcutaneous injection
- Mild nasal irritation is common in the first week
- Not suitable during an active sinus infection
- Human data for the intranasal route specifically is limited
Regulatory status: Compounded. Read our full medical disclaimer.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. This product is compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Actual product packaging may appear differently than shown.
What is NAD+ Nasal Spray?
The nasal mucosa is unusually permeable and sits directly beneath the olfactory nerve pathway.
Compounds absorbed here can reach the central nervous system along that pathway, partially circumventing the blood-brain barrier that limits systemic delivery.
Individual results vary. Figures shown are modelled from published literature and aggregated, self-reported member check-ins; they are illustrative and are not a guarantee of outcome. See the evidence tier for this treatment.
days to a fair assessment
90How NAD+ Nasal Spray works
Week 1
Onboarding, first dose and a check-in on tolerability. Most protocols start below the standard dose so your body has time to adjust.
30 Days
Your first real signal. We review side effects, adherence and any early changes before deciding whether to adjust anything.
3 Months
The window where most measurable change shows up. Repeat labs where the protocol calls for them, and a dose review either way.
6 Months
Trend lines rather than single readings. We compare against your baseline panel and decide whether to continue, adjust or stop.
1 Year and Beyond
Maintenance. The goal is the lowest effective dose you can hold, with twice-yearly labs keeping the protocol honest.
Our research is shaping what comes next
Most providers in this category focus on doing more. We study what happens when the goal is finding the right amount. With a fully in-house care team, longevity researchers, and 17+ protocols graded by evidence tier, we're built to support the bigger picture of your health.
Intranasal delivery to the central nervous system
Journal of Controlled Release · 2020
NAD+ metabolism in neurodegeneration and ageing
Nature Reviews Neuroscience · 2022
Nose-to-brain transport pathways
Advanced Drug Delivery Reviews · 2019
NAD+ Nasal Spray
treatment insights
Modelled response patterns are trending in the optimal range
Read our clinical trials
Cellular energy and longevity
Our researchers are studying nad+ nasal spray through a longevity-focused lens, exploring how lower-dose protocols may be used in long-horizon care beyond the primary indication.
Read our researchSubscribe & save
Care that starts
with you
$49/month
What's included
- Personalized, clinician-guided plan
- Flexible monthly plans
- Dispensed by a US-licensed pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Third-party potency and sterility testing
How it works
Choosing how you age starts here
- Certified1
Clinician-led
Connect with a clinician
Connect with one of our US-licensed, in-house medical providers with 199+ years of combined clinical experience to make sure treatment is right for you. 100% online. No in-person visit required.
- 2
Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed pharmacy, third-party tested by lot, and shipped to your door in unbranded packaging — cold-chain where the formulation requires it.
- 3
Ongoing support
Adjust as you go
Message your care team whenever something changes. Dose adjustments, side-effect questions and protocol changes are included in your membership — never another appointment, never another fee.
The protocol
- Typical dose
- 1–2 sprays per nostril daily
- Route
- Intranasal
- Onset
- 2–4 weeks for most
- Storage
- Refrigerate between uses
- Shipping
- Monthly, refrigerated
A good fit if
- You want NAD+ support without injections
- Cognitive symptoms are your primary complaint
- You travel frequently
- You want to try NAD+ before committing to injections
Worth knowing
- Lower systemic exposure than subcutaneous injection
- Mild nasal irritation is common in the first week
- Not suitable during an active sinus infection
- Human data for the intranasal route specifically is limited
Ready when you are
Start NAD+ Nasal Spray today
Complete a ten-minute intake, get a licensed clinician's review, and find out whether this is right for you — before you pay for anything.