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The evidence, plainly stated
Written by our clinicians and research team. We tell you where the data is strong, where it's thin, and where we're making a considered bet.
Everything else
Metabolic health
Muscle is the point
Losing weight is easy to measure and easy to get wrong. The composition of what you lose determines whether the result holds.
June 30, 2026 · 6 min read
Protocols
What happens when you stop a GLP-1
Regain is the most predictable thing about these medications, and the least planned for. Here's the exit strategy.
May 18, 2026 · 6 min read
Science
NAD+: what the evidence actually supports
An honest read on one of the most hyped compounds in longevity — where the mechanistic case is strong and where the human data runs out.
August 4, 2026 · 8 min read
Science
Peptides, explained without the hype
What a peptide actually is, why this category exploded, and how to tell the well-studied compounds from the ones riding the wave.
April 11, 2026 · 9 min read
Longevity
The five markers that matter more than your cholesterol number
Standard panels were built to detect disease. These five detect the drift that precedes it by a decade.
March 26, 2026 · 7 min read
Longevity
Biological age: useful signal or expensive horoscope?
Epigenetic clocks are real science with real limitations. What they measure, what they don't, and how much to weight the number.
February 14, 2026 · 7 min read
Guides
How to read a study before you believe a headline
Six questions that will resolve most longevity claims in under five minutes, without a science degree.
January 20, 2026 · 6 min read
Metabolic health
Food noise, explained
The constant background negotiation with food has a physiology. Understanding it explains why willpower framing fails.
December 9, 2025 · 5 min read
Protocols
Sleep is the first intervention, not the last
Every protocol we prescribe works worse on six hours. Here's why sleep gets fixed before anything else.
November 15, 2025 · 6 min read
Science
The perimenopause timeline nobody explains
The decade before menopause is where most symptoms live — and where most women are told their labs are normal.
October 28, 2025 · 8 min read
Guides
What "compounded" actually means
A large share of what this industry sells is compounded. Here's what that means for quality, legality and your risk.
September 30, 2025 · 6 min read
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