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Recovery & repair
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TB-500 Rx

Often paired with BPC-157 for stubborn soft-tissue injuries, with research centered on cell migration, flexibility and inflammatory modulation.

  • Complements BPC-157
  • Studied for flexibility
  • Inflammatory modulation
  • Flexible monthly plans
  • US-licensed pharmacies
  • Clinician-guided dosing
  • Pause or cancel anytime

Starting at$110 / mo

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  • HSA / FSA eligible
  • Ongoing, expert support
  • Free, discreet shipping
  • 100% online

Why is it usually stacked with BPC-157?
They target different steps. BPC-157 research centers on new blood-vessel formation; TB-500 research centers on cell migration into the site. Clinicians often use them together for that reason.
What's the loading phase for?
Higher twice-weekly dosing for the first four weeks is intended to reach effective tissue levels faster, after which a weekly maintenance dose holds it.
Can I train while cycling it?
Usually yes, but the loading schedule matters. Your clinician will set a return-to-load progression so you don't undo the repair.

Injection-site reactions, transient fatigue in the loading phase and occasional headache are the commonly reported effects. As with other research peptides, the limited long-term human data is the primary consideration.

Who this is not for

  • Not FDA-approved; human evidence is limited
  • Prohibited by WADA in and out of competition
  • Contraindicated with active malignancy
  • Not evaluated in pregnancy or breastfeeding

Regulatory status: Compounded. Read our full medical disclaimer.

Disclaimer

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. This product is compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Actual product packaging may appear differently than shown.

What is TB-500?

TB-500 is a synthetic fragment of thymosin beta-4, a protein present in nearly all human cells and highly concentrated at wound sites.

Its central proposed action is binding actin — the structural protein cells use to move — which supports the cell migration required to populate and rebuild damaged tissue.

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Individual results vary. Figures shown are modelled from published literature and aggregated, self-reported member check-ins; they are illustrative and are not a guarantee of outcome. See the evidence tier for this treatment.

days to a fair assessment

90
Change03mo6mo12mo
Reported change from baseline

How TB-500 works

  1. Week 1

    Onboarding, first dose and a check-in on tolerability. Most protocols start below the standard dose so your body has time to adjust.

  2. 30 Days

    Your first real signal. We review side effects, adherence and any early changes before deciding whether to adjust anything.

  3. 3 Months

    The window where most measurable change shows up. Repeat labs where the protocol calls for them, and a dose review either way.

  4. 6 Months

    Trend lines rather than single readings. We compare against your baseline panel and decide whether to continue, adjust or stop.

  5. 1 Year and Beyond

    Maintenance. The goal is the lowest effective dose you can hold, with twice-yearly labs keeping the protocol honest.

Our research is shaping what comes next

Most providers in this category focus on doing more. We study what happens when the goal is finding the right amount. With a fully in-house care team, longevity researchers, and 17+ protocols graded by evidence tier, we're built to support the bigger picture of your health.

  • Thymosin beta-4 in tissue repair and regeneration

    Annals of the New York Academy of Sciences · 2012

  • Actin-sequestering peptides and cell migration

    Journal of Cell Science · 2015

  • Thymosin beta-4 in cardiac and dermal repair models

    Expert Opinion on Biological Therapy · 2018

Read our research

TB-500
treatment insights

Optimal

Modelled response patterns are trending in the optimal range

03mo6mo12mo

Read our clinical trials

Recovery & repair and longevity

Our researchers are studying tb-500 through a longevity-focused lens, exploring how lower-dose protocols may be used in long-horizon care beyond the primary indication.

Read our research

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Care that starts
with you

$110/month

What's included

  • Personalized, clinician-guided plan
  • Flexible monthly plans
  • Dispensed by a US-licensed pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Third-party potency and sterility testing
Get Started

How it works

Choosing how you age starts here

  1. Certified

    Clinician-led

    Connect with a clinician

    Connect with one of our US-licensed, in-house medical providers with 199+ years of combined clinical experience to make sure treatment is right for you. 100% online. No in-person visit required.

  2. Fast, discreet shipping

    Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed pharmacy, third-party tested by lot, and shipped to your door in unbranded packaging — cold-chain where the formulation requires it.

  3. Ongoing support

    Adjust as you go

    Message your care team whenever something changes. Dose adjustments, side-effect questions and protocol changes are included in your membership — never another appointment, never another fee.

The protocol

Loading phase
2–2.5 mg twice weekly, 4 weeks
Maintenance
2 mg weekly
Route
Subcutaneous injection
Cycle length
6–12 weeks
Shipping
Monthly, refrigerated

A good fit if

  • A chronic soft-tissue injury with a long healing timeline
  • You're already running BPC-157 and have plateaued
  • Range-of-motion limits around an old injury
  • You prefer fewer injections per week

Worth knowing

  • Not FDA-approved; human evidence is limited
  • Prohibited by WADA in and out of competition
  • Contraindicated with active malignancy
  • Not evaluated in pregnancy or breastfeeding

Ready when you are

Start TB-500 today

Complete a ten-minute intake, get a licensed clinician's review, and find out whether this is right for you — before you pay for anything.

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