Sermorelin Rx
Rather than replacing growth hormone, sermorelin prompts your pituitary to produce its own — preserving the natural overnight pulse and its feedback loop.
- Preserves natural rhythm
- Deeper sleep reported
- Recovery and body composition
- Flexible monthly plans
- US-licensed pharmacies
- Clinician-guided dosing
- Pause or cancel anytime
Starting at$129 / mo
- HSA / FSA eligible
- Ongoing, expert support
- Free, discreet shipping
- 100% online
- How is this different from taking HGH?
- HGH replaces the hormone directly and suppresses your own production. Sermorelin stimulates your pituitary to make more of its own, which preserves the pulse pattern and the feedback loop that caps it.
- Why at night and on an empty stomach?
- The natural growth-hormone pulse happens in early deep sleep, and elevated insulin blunts the response. Taking it at bedtime, a couple of hours after eating, works with both.
- How long before I see anything?
- Sleep quality often changes within a few weeks. Body-composition changes are a three-to-six-month conversation, and we'll check IGF-1 along the way.
Injection-site redness, flushing and vivid dreams are the most frequent reports. Water retention and joint aching can occur and generally indicate the dose should come down.
Who this is not for
- Contraindicated with active malignancy
- Requires baseline IGF-1 testing and periodic monitoring
- Must be taken away from food to be effective
- Not evaluated in pregnancy or breastfeeding
Regulatory status: Compounded. Read our full medical disclaimer.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. This product is compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Actual product packaging may appear differently than shown.
What is Sermorelin?
(ser-moh-REL-in)
Sermorelin is a 29-amino-acid analog of growth-hormone-releasing hormone, the signal your hypothalamus sends to the pituitary.
Given at night, it amplifies the natural overnight growth-hormone pulse rather than replacing it with a flat exogenous level.
Individual results vary. Figures shown are modelled from published literature and aggregated, self-reported member check-ins; they are illustrative and are not a guarantee of outcome. See the evidence tier for this treatment.
reported deeper, less fragmented sleep
41%How Sermorelin works
Week 1
Nightly dosing on an empty stomach. Vivid dreams and injection-site flushing are the usual first-week reports.
30 Days
Sleep quality is typically the first thing to change, and the first thing patients notice.
3 Months
Recovery between training sessions is usually the next change. IGF-1 gets re-checked around here.
6 Months
Body-composition changes, if they're coming, are visible by now. Dose adjusted against IGF-1.
1 Year and Beyond
Cycled with planned breaks, monitored twice yearly, and stopped if the markers stop justifying it.
Our research is shaping what comes next
Most providers in this category focus on doing more. We study what happens when the goal is finding the right amount. With a fully in-house care team, longevity researchers, and 17+ protocols graded by evidence tier, we're built to support the bigger picture of your health.
Growth hormone-releasing hormone analogs in adults
Journal of Clinical Endocrinology & Metabolism · 2010
GHRH, slow-wave sleep and the somatotropic axis
Sleep Medicine Reviews · 2016
Growth hormone secretagogues and body composition
Endocrine Reviews · 2019
Sermorelin
treatment insights
Modelled response patterns are trending in the optimal range
Read our clinical trials
Growth hormone axis and longevity
Our researchers are studying sermorelin through a longevity-focused lens, exploring how lower-dose protocols may be used in long-horizon care beyond the primary indication.
Read our researchSubscribe & save
Care that starts
with you
$129/month
What's included
- Personalized, clinician-guided plan
- Flexible monthly plans
- Dispensed by a US-licensed pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Third-party potency and sterility testing
How it works
Choosing how you age starts here
- Certified1
Clinician-led
Connect with a clinician
Connect with one of our US-licensed, in-house medical providers with 199+ years of combined clinical experience to make sure treatment is right for you. 100% online. No in-person visit required.
- 2
Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed pharmacy, third-party tested by lot, and shipped to your door in unbranded packaging — cold-chain where the formulation requires it.
- 3
Ongoing support
Adjust as you go
Message your care team whenever something changes. Dose adjustments, side-effect questions and protocol changes are included in your membership — never another appointment, never another fee.
The protocol
- Typical dose
- 200–300 mcg nightly
- Timing
- At bedtime, on an empty stomach
- Route
- Subcutaneous injection
- Cycling
- 5 nights on, 2 off is common
- Onset
- Sleep changes in weeks; composition in months
A good fit if
- Declining recovery capacity with age
- Poor sleep quality alongside training fatigue
- You want growth-axis support without direct HGH
- You're prepared for a months-long timeline
Worth knowing
- Contraindicated with active malignancy
- Requires baseline IGF-1 testing and periodic monitoring
- Must be taken away from food to be effective
- Not evaluated in pregnancy or breastfeeding
Ready when you are
Start Sermorelin today
Complete a ten-minute intake, get a licensed clinician's review, and find out whether this is right for you — before you pay for anything.